Jacquet Maxime
Ph D student
Research
My research will focus on the ecology of Borrelia afzelii, one of the most important agents of Lyme disease in Europe (including Switzerland). This pathogen is predominantly found in wild animals (such as rodents and mice) and is transmitted via its tick vector, Ixodes ricinus.
Recent work on B. afzelii found that there are two possible modes of transmission between the vertebrate host and the tick vector. In systemic transmission, the host develops a chronic infection that can be transmitted many weeks or even months later to blood-feeding ticks. In co-feeding transmission, the bacteria can pass directly between infected and uninfected ticks that are feeding in close proximity to each other (i.e without necessarily establishing a systemic infection). Some strains of B. afzelii appear to be capable of both modes of transmission whereas other strains only use the systemic mode.
There is currently much interest in vaccinating wild rodents to reduce the density of Borrelia-infected ticks and thus the human risk of Lyme diseases. One of these vaccines targets Borrelia outer surface protein C (ospC), which is critical for the bacteria to invade the vertebrate host. It is currently not clear whether strains transmitted via co-feeding express this outer surface protein. Similarly, it is not clear whether such strains would be eliminated in ospC-vaccinated mice or whether they would "escape" from the vaccine. I am therefore interested in studying how vaccines change the selective landscape and select for alternative modes of transmission.
Teaching Responsabilities
Teaching pratical courses in statistics (third year Bachelor students) and in histology (first year Bachelor students in medical science).
PUBLICATIONS
2015
Jacquet M , Tilquin M, Ravanel P,Boyer S. 2015. Increase in Tolerance of Aedes aegypti Larvae (Diptera: Culicidae) to the Insecticide Temephos after Exposure to Atrazine. African Journal of Entomology. reference.sabinet.co.za/sa_epublication_article/ento_v23_n1_a12
2014
Srisawat R., Sungvornyothin S., Jacquet M. et al. 2014. Preserving blood-fed Aedes albopictus from field to laboratory for blood source determination. JITMM Proceedings. http://www.jitmm.com/proceeding/compPaper/2014/Raweewan.pdf
2013
Oliva CF, Maier MJ, Gilles J, Jacquet M, Lemperiere G, Quilici S, et al. 2012. Effects of irradiation, presence of females, and sugar supply on the longevity of sterile males Aedes albopictus (Skuse) under semi-field conditions on Reunion Island. Acta tropica. Epub 2012/12/05 www.sciencedirect.com/science/article/pii/S0001706X12003749
2012
Jacquet, M., Harala, E., Lemperiere, G. and Poteri, M. 2013.Preliminary Results of a Slow Release Formulation of Imidacloprid for the Control of the Large Pine Weevil (Hylobius abietis L.) Baltic Forestry 18(1): 83-90. www.balticforestry.mi.lt/bf/index.php
Boyer S, Toty C, Jacquet M, Lempérière G, Fontenille D (2012) Evidence of Multiple Inseminations in the Field in Aedes albopictus. PLoS ONE 7(8): e42040. doi:10.13 journals.plos.org/plosone/article
Jacquet M, Lebon C, Lemperiere G, Boyer S. (2012). Behavioural functions of grooming in male Aedes albopictus (Diptera: Culicidae), the Asian tiger mosquito. Applied Entomology and Zoology DOI 10.1007-012-0126-6 link.springer.com/article/10.1007%2Fs13355-012-0126-6 ///
Oliva CF, Jacquet M, Gilles J, Lemperiere G, Maquart P-O, et al. (2012) The Sterile Insect Technique for Controlling Populations of Aedes albopictus (Diptera: Culicidae) on Reunion Island: Mating Vigour of Sterilized Males. PLos ONE 7(11): e49414. doi:10.1371 journals.plos.org/plosone/article
