Diego Gonzalez
SNSF Ambizione fellow
Carrier and research interests
Trained as a microbiologist and molecular biologist, I am pursuing an academic carrier at the crossroad of microbiology and evolutionary biology.
I obtained a PhD from the University of Lausanne in 2013 studying the molecular clockwork of bacterial regulatory processes, including DNA methylation and small molecules. After a postdoctoral research time in Oxford and Lausanne dedicated to bacterial evolution, I settled in the Laboratoire de Microbiologie of the University of Neuchâtel, where I am leading a small research group since autumn 2018. Overall, the aim of my group is to shed light on bacterial rhythmic behaviors and to gain a better understanding of the evolutionary dynamics of microbial communities.
See the project webpage for further details.
Academic curriculum
- 2018 – to date SNSF Ambizione fellow
Laboratoire de Microbiologie, University of Neuchâtel, Switzerland
- 2017 – 2018 Postdoctoral fellow (group of Prof. Philipp Engel)
Department of Microbiology, University of Lausanne, Switzerland
- 2015 – 2017 Postdoctoral fellow (group of Prof. Kevin Foster)
Department of Zoology of the University of Oxford, United Kingdom
- 2013 – 2014 Postdoctoral fellow (group of Dr Justine Collier)
Department of Microbiology, University of Lausanne, Switzerland
- 2013 PhD in Life Sciences (group of Dr Justine Collier)
Department of Microbiology, University of Lausanne, Switzerland
- 2010 Master in Experimental biology and bioinformatics
Department of Microbiology, University of Lausanne, Switzerland
Publications
* : First co-authors. % : Co-corresponding authors. # : five most significant
As First Author, from the postdoctoral research:
- Gonzalez Diego%, Akshay Sabnis, Kevin R. Foster, Despoina A. Mavridou% , “Costs and benefits of provocation in bacterial warfare” (2018), PNAS, 115(29):7593-7598. #[https://www.cell.com/current-biology/fulltext/S0960-9822(17)31663-9]
- Gonzalez Diego*, Despoina A. Mavridou*, Wook Kim, Stuart A. West, Kevin R. Foster (2018), “Bacteria use collective behavior to generate diverse combat strategies”, Current Biology, 28 (3): 345-355. # [https://www.cell.com/current-biology/fulltext/S0960-9822(17)31663-9]
- Gonzalez Diego*, Despoina A. Mavridou*, Abigail Clements and Kevin R. Foster (2016), “The pUltra plasmid series: A robust and flexible tool for fluorescent labeling of Enterobacteria”, Plasmid, 87-88: 65-71. [http://www.sciencedirect.com/science/article/pii/S0147619X16300671]
As First Author, from the PhD:
- Gonzalez Diego and Justine Collier (2015), “Genomic Adaptations to the Loss of a Conserved Bacterial DNA Methyltransferase”, MBio, 6 (4): e00952. # [http://mbio.asm.org/content/6/4/e00952-15.abstract]
- Gonzalez Diego and Justine Collier (2014), “Effects of (p)ppGpp on the progression of the cell cycle of Caulobacter crescentus”, Journal of Bacteriology, 196 (14): 2514-25. (#) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097592]
- Gonzalez Diego, Jennifer B. Kozdon, Harley H. McAdams, Lucy Shapiro and Justine Collier (2014), “The functions of DNA methylation by CcrM in Caulobacter crescentus: a global approach”, Nucleic Acids Research, 42 (6):3720-35. # [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973325]
- Gonzalez Diego and Justine Collier (2013), “DNA methylation by CcrM activates the transcription of two genes required for the division of Caulobacter crescentus”, Molecular Microbiology, 88 (1): 203-218. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708114]
As Author, from the PhD:
- Shevket Shevket H., Diego Gonzalez, Jared L. Cartwright, Colin Kleanthous, Stuart J. Ferguson, Christina Redfield, Despoina A. Mavridou (2018), “The CcmC-CcmE interaction during cytochrome c maturation by System I is driven by protein-protein and not protein-heme contacts”, Journal of Biological Chemistry, 293(43): 16778-16790. [http://www.jbc.org/content/293/43/16778.long]
- Gallego-García Aranza, Antonio A. Iniesta, Diego González, Justine Collier, S. Padmanabhan, Montserrat Elías-Arnanz (2017), “Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription”, Scientific Reports, 7: 43240. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324124]
- Kozdon Jennifer B., Michael D. Melfi, Khai Luong, Tyson A. Clark, Matthew Boitano, Susana Wang, Bo Zhou, Diego Gonzalez, Justine Collier, Stephen W. Turner, Jonas Korlach, Lucy Shapiro, Harley H. McAdams (2013), “Global methylation state at base pair resolution of the Caulobacter genome throughout the cell cycle”, PNAS, 110 (48): E4658-67. [http://www.pnas.org/content/110/48/E4658.abstract]
- Fernandez-Fernandez Carmen, Diego Gonzalez and Justine Collier (2011), “Regulation of the Activity of the Dual-Function DnaA Protein in Caulobacter crescentus”, PLoS One, 6 (10): e26028. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193534]
Reviews, from the postdoctoral research time:
- Diego Gonzalez and Despoina A. Mavridou (2019), “Making the Best of Aggression: The Many Dimensions of Bacterial Toxin Regulation”, Trends in Microbiology, 27(11): 897-905.
[https://www.cell.com/trends/microbiology/fulltext/S0966-842X(19)30150-7]
- Valentini Martina, Diego Gonzalez, Despoina Mavridou. and Alain Filloux (2018), “Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa”, Current Opinions in Microbiology, 41: 15-20. [https://www.sciencedirect.com/science/article/abs/pii/S1369527417301613]